Cattle Drive Casserole Recipe : Easy Ground Beef Dinner in 45 Minutes

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Are you searching for quick dinner ideas that don’t compromise on flavor? Look no further than this mouthwatering Cattle Drive Casserole! This hearty, layered dish combines seasoned ground beef, a golden biscuit crust, creamy sour cream mixture, and melted cheddar cheese into one unforgettable meal. Whether you’re feeding a hungry family after a long day or hosting a casual dinner party, this recipe delivers big on taste while keeping preparation simple and stress-free.

What makes this casserole special is its perfect balance of textures and flavors. The buttery biscuit base provides a satisfying foundation, while the spiced ground beef layer brings bold, savory notes. The creamy middle layer adds richness, and the melted cheese topping creates that irresistible golden finish we all crave. Plus, with just 45 minutes from start to finish, it’s one of those easy meals with ground beef that proves comfort food doesn’t have to be complicated.

Table of Contents

Why You’ll Love This Cattle Drive Casserole

This recipe checks all the boxes for busy home cooks:

  • Quick preparation: Ready in just 45 minutes, making it perfect for weeknight dinners
  • Budget-friendly: Uses affordable ground beef and pantry staples
  • Family-approved: Kid-friendly flavors that please picky eaters
  • Make-ahead friendly: Prepare components in advance for even easier assembly
  • Customizable: Easy to adjust spice levels and add your favorite toppings
  • One-dish wonder: Minimal cleanup with everything baked in a single casserole dish

Whether you’re new to cooking or a seasoned home chef, this ground meat recipe for dinner will become your go-to comfort food solution.

Essential Equipment for This Recipe

Before starting, gather these key tools to make preparation smooth:

Having the right equipment makes this hamburger meat recipe even easier to execute perfectly.

Ingredient Breakdown

For the Biscuit Base

IngredientQuantity
Biscuit Mix (like Bisquick)2 ½ cups
Water1 cup
Cooking Sprayas needed

For the Beef Layer

IngredientQuantity
Lean Ground Beef1.5 pounds
Red Bell Pepper (chopped)1 medium
Yellow Onion (chopped)1 medium
Taco Seasoning Mix1 ounce

For the Creamy Layer

IngredientQuantity
Sour Cream½ cup
Mayonnaise½ cup
Diced Green Chiles (drained)4 ounces
Cheddar Cheese (shredded, divided)1 ½ cups
Garlic Powder1 teaspoon

For the Topping

IngredientQuantity
Mild Salsa½ cup
Remaining Cheese¾ cup

Step-by-Step Instructions

Preparing Your Kitchen

  1. Preheat your oven to 350℉ to ensure even baking
  2. Gather all ingredients on your cutting board and workspace
  3. Spray your casserole dish with cooking spray to prevent sticking

Making the Biscuit Base

  1. Combine biscuit mix and water in a mixing bowl. Use your hands to thoroughly mix until a soft dough forms
  2. Press the dough into the prepared casserole dish, spreading it evenly to all edges
  3. Bake for 5-8 minutes until the crust is set and lightly golden. Remove and set aside, keeping the oven on

Cooking the Beef Layer

  1. Heat your frying pan over medium-high heat
  2. Add ground beef and break it apart with a wooden spoon. Cook until no longer pink, about 6-8 minutes
  3. Drain excess fat using a colander if necessary
  4. Add chopped onions and bell pepper to the beef. Cook for 4 minutes, stirring occasionally, using ingredients prepped on your cutting board
  5. Stir in taco seasoning mix until the meat is well-coated. Remove from heat
  6. Spread the beef mixture evenly over the baked biscuit crust, reaching all edges

Creating the Creamy Layer

  1. Combine sour cream, mayonnaise, drained green chiles, ¾ cup shredded cheese, and garlic powder in a clean mixing bowl
  2. Mix thoroughly using a kitchen utensil until well blended
  3. Carefully spread this creamy mixture over the beef layer as evenly as possible

Final Assembly and Baking

  1. Add small spoonfuls of salsa across the top of the creamy layer no need to spread it completely
  2. Sprinkle the remaining ¾ cup of cheese evenly over everything
  3. Bake uncovered for 30 minutes until the casserole is hot, bubbly, and the cheese is melted and golden

Serving

  1. Let the casserole rest for 5 minutes after removing from the oven
  2. Cut into squares and serve hot with your favorite toppings

Pro Tips for Perfect Results

Choose quality ground beef: Opt for 90% lean ground beef to minimize excess grease while maintaining flavor and moisture.

Don’t skip the vegetable sauté: Cooking the onions and peppers with the beef adds depth and sweetness to the overall dish.

Adjust spice levels: Use mild, medium, or hot salsa depending on your family’s preference. You can also substitute jalapeños for green chiles if you want more heat.

Make ahead option: Prepare the casserole up to the final baking step, cover tightly with foil, and refrigerate for up to 24 hours. Add 10 extra minutes to baking time if cooking from cold.

Prevent soggy crust: Make sure to bake the biscuit layer first until it’s set. This creates a barrier that keeps it from becoming soggy when topped with the beef mixture.

Use fresh cheese: Shred your own cheese from a block rather than using pre-shredded for better melting and flavor.

Serving Suggestions

This Cattle Drive Casserole pairs beautifully with:

  • Fresh green salad with ranch dressing
  • Mexican rice or cilantro lime rice
  • Tortilla chips and guacamole
  • Corn on the cob or roasted vegetables
  • Refried beans or black beans

Storage and Reheating

Refrigerator: Store leftovers in an airtight container for up to 4 days. Reheat individual portions in the microwave for 2-3 minutes or reheat the entire casserole covered in a 350℉ oven for 20 minutes.

Freezer: This casserole freezes well for up to 3 months. Wrap tightly in plastic wrap, then foil. Thaw overnight in the refrigerator before reheating.

Reheating tip: Add a tablespoon of water or broth before reheating to prevent drying out.

Frequently Asked Questions

Can I use ground turkey or chicken instead of beef?
Absolutely! Ground turkey or ground chicken work perfectly in this recipe. You may want to add a tablespoon of oil to the pan since these meats are leaner and can stick more easily.

What if I don’t have biscuit mix?
You can make your own by combining 2 ½ cups all-purpose flour, 1 tablespoon baking powder, ½ teaspoon salt, and ⅓ cup cold butter cut into the flour mixture. Add 1 cup milk instead of water.

Can I make this casserole vegetarian?
Yes! Replace the ground beef with black beans, pinto beans, or a plant-based ground meat alternative. The rest of the recipe remains the same.

How do I know when the casserole is done?
The casserole is ready when the cheese is melted and bubbly, and the edges are lightly golden. An instant-read thermometer should register at least 165℉ in the center.

Can I double this recipe?
Certainly! Use two 9×13-inch casserole dishes or one very large baking dish. Keep the same baking time but check for doneness, as a thicker casserole may need a few extra minutes.

What other cheeses work well?
Monterey Jack, pepper jack, Mexican blend, or a combination of cheddar and mozzarella all work wonderfully. Choose based on your preferred flavor profile and heat level.

Why This Recipe Works

The genius of this Cattle Drive Casserole lies in its construction. The biscuit base acts as both a crust and a flavor vehicle, absorbing the savory juices from the beef while maintaining structural integrity. The taco-seasoned meat provides bold, familiar flavors that appeal to all ages. The creamy middle layer adds richness and helps bind the components together, while the cheese topping creates that irresistible golden, bubbly finish.

This recipe represents everything great about easy hamburger meat recipes: minimal prep work, accessible ingredients, crowd-pleasing flavors, and foolproof techniques. It’s a testament to how simple ground beef can be transformed into something truly special with the right combination of ingredients and cooking methods.

Final Thoughts

Whether you’re looking for lazy dinners that don’t sacrifice flavor or planning your weekly meal prep, this Cattle Drive Casserole delivers on all fronts. It’s hearty enough to satisfy hungry appetites, simple enough for beginner cooks, and delicious enough to earn regular rotation in your dinner repertoire.

The beauty of this recipe is its adaptability feel free to experiment with different vegetables, adjust the spice level to your liking, or add your favorite toppings like sliced olives, diced tomatoes, or fresh cilantro. Each variation will bring its own unique twist while maintaining the comforting essence that makes this casserole so special.

So grab your frying pan, mixing bowls, and casserole dish, and get ready to create a dinner that will have everyone asking for seconds!

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